前列腺癌骨转移研究进展

骨骼是最常见的前列腺癌转移靶器官,前列腺癌骨转移是一系列复杂而有序的过程,其发生机制可能涉及多个方面。现就从解剖学、病理学、分子生物学等方面对前列腺癌骨转移机制的研究现状作一综述。

Bone metastasis of prostate cancer: An update

Prostate cancer shows a strong predilection to spread to the bones.Cancer metastasis is composed of a complex cascade that involves a variety of critical steps beginning with detachment from the primary tumor and ending with growth of the tumor at a distant site.Varous factors produced by the bone microenvironment contribute to the pathogenesis of cancer skeletal metastasis.This review summarizes the multifactorial mechanisms and complex cellular interactions that take place inside the bone metastatic micro...