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ELISA抗梅毒螺旋体抗原的特异性IgG/IgM抗体在诊断梅毒中的应用
引用本文:孙乐栋,周再高,曾抗,江丽芬,谭仲楷,张健秀.ELISA抗梅毒螺旋体抗原的特异性IgG/IgM抗体在诊断梅毒中的应用[J].中国中西医结合皮肤性病学杂志,2002,1(1):39-40.
作者姓名:孙乐栋  周再高  曾抗  江丽芬  谭仲楷  张健秀
作者单位:广州第一军医大学南方医院皮肤科,广州,510515
摘    要:目的探讨酶联免疫吸附测定(ELISA)抗梅毒螺旋体抗原的特异性IgG/IgM抗体在诊断梅毒中的应用。方法临床诊断或怀疑为梅毒的97例患者和74例非梅毒患者的血清同时接受ELISA抗梅毒螺旋体抗原的特异性IgG/IgM抗体和TPPA试验两种检测。结果ELISA抗梅毒螺旋体抗原的特异性IgG/IgM抗体具有较高的敏感性和特异性。结论ELISA抗梅毒螺旋体抗原的特异性IgG/IgM抗体适合于大样本的筛查和确诊。

关 键 词:梅毒  酶联免疫吸附测定  梅毒螺旋体被动乳胶凝集试验
文章编号:1672-0709(2002)01-0039-02
修稿时间:2002年5月29日

Application of Enzyme Immumoassays for Detection of IgG/IgM to Trgeponema Pallidum in Diagnosis of Syphilis
SUN Le-dong,ZHOU Zai-gao,ZENG kang,JIANG Li-fen,TAN Zhong-kai,ZHANG Jian-xiu.Application of Enzyme Immumoassays for Detection of IgG/IgM to Trgeponema Pallidum in Diagnosis of Syphilis[J].Chinese J of Dermatovenerology Integr Tradit and West Med,2002,1(1):39-40.
Authors:SUN Le-dong  ZHOU Zai-gao  ZENG kang  JIANG Li-fen  TAN Zhong-kai  ZHANG Jian-xiu
Institution:SUN Le-dong,ZHOU Zai-gao,ZENG kang,JIANG Li-fen,TAN Zhong-kai,ZHANG Jian-xiu Department of Dermatology,Nanfang Hospital of the First Military Medical University,Guangzhou510515,China
Abstract:objective To evaluate the effect of enzyme immumoassays(ELISA)for detection of IgG/IgM to trge-ponema pallidum in diagnosis of syphilis.Methods Serum samples of97patients with syphilis suspicious or suspicious syphilis and serum samples of74patients without syphilis were tested by ELISA for detection of IgG/IgM to trgeponema pallidum and TPPA,respectively.Results ELISA for detection of IgG/IgM to trgeponema pallidum had both high sensi-tivity and high speciticity in diagnosis of syphilis.Conclusion ELISA for detection of IgG/IgM to trgeponema pallidum can be used not only in screen syphilis for large samples,but also in determinating diagnosis of syphilis.
Keywords:syphilis  ELISA  TPPA
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