A new lignan glucoside from the stems of Callicarpa japonica Thunb. var. luxurians Rehd. |
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| Authors: | Masateru Ono Kenji Mishima Toru Yamasaki Chikako Masuoka Masafumi Okawa Junei Kinjo Tsuyoshi Ikeda Toshihiro Nohara |
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| Affiliation: | (1) School of Agriculture, Tokai University, 5435 Minamiaso, Aso, Kumamoto 869-1404, Japan;(2) Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan;(3) Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862-0973, Japan;(4) Faculty of Pharmaceutical Sciences, Sojo University, 4-22-1 Ikeda, Kumamoto 860-0082, Japan |
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| Abstract: | ![]()
A new lignan glucoside (1) was isolated from the stems of Callicarpa japonica Thunb. var. luxurians Rehd. (Verbenaceae), along with six known lignan glucosides and three known triterpenoids. The chemical structure of 1 was characterized as (+)-lyoniresinol 3α-O-(6″-3,5-dimethoxy-4-hydroxybenzoyl)-β-d-glucopyranoside on the basis of spectroscopic data. In addition, the radical-scavenging effect of four lignans on the stable free radical 1,1-diphenyl-2-picrylhydrazyl was examined. Among the tested compounds, three compounds, including 1, showed almost the same scavenging activity as that of α-tocopherol. |
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| Keywords: | Callicarpa japonica Thunb. var. luxurians Rehd. Verbenaceae Lignan glucoside Triterpenoid Radical-scavenging effect |
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