776例甲状腺肿块术中冰冻切片诊断分析

目的:探讨甲状腺肿块冰冻切片诊断的临床意义及其误诊原因。方法:分析1995年12月至2003年7月术中776例甲状腺肿块冰冻切片与术后石蜡切片的诊断结果。结果:776例中,确诊758例,确诊率为97.7%;误诊15例,误诊率为1.9%;甲状腺癌131例,其中假阴性漏诊14例,漏诊率10.7%。结论:术中冰冻切片对甲状腺占位病变有定性诊断意义,但取材的局限性,病变形态的多样性,隐匿性和冰冻切片的质量是造成漏诊和延迟诊断的主要原因。

Diagnosis value of intraoperative frozen section in thyroid neoplasms: Analysis of 776 cases

Objective: To Analysis the clinical significance of frozen section for the diagnosis of thyroid neoplasms and discuss the cause of wrong diagnosis. Methods: The diagnostic reports of intraoperative frozen sections and paraffin sections were analyzed retrospectively in 776 cases with thyroid neoplasms since Oct 1995 to Jul 2003. Results: The original diagnosis of frozen section was accurate in 758 of 776 cases (97.7%) wrong diagnosis in 15 of 776 (1.9%). False of negative in thyroid carcinoma is 14 of 131(10.7%). Conclusions: Frozen section is valuable in the diagnosis of thyroid neoplasms and is important for the choice of operation method. The factors affecting the caccuracy of frozen section diagnosis includes the qulity of the section, the diversity of the disease and the limition of the section material.