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糖尿病鼠模型研究新进展
引用本文:陈郊丽,YANG Ying.糖尿病鼠模型研究新进展[J].昆明医学院学报,2012,33(2):144-146.
作者姓名:陈郊丽  YANG Ying
作者单位:云南省第二人民医院,昆明医学院第四附属医院内分泌与代谢病科,云南,昆明,650021
基金项目:国家自然科学基金,云南省中青年学术技术带头人后备人才基金
摘    要:建立理想的动物模型是对糖尿病病因、发病机理及其药物治疗进行研究的重要途径.糖尿病鼠模型的制备方法 可以分为自发性、实验性诱发模型、转基因模型等,各有其特点.对1、2型糖尿病鼠模型研究新进展做一综述.

关 键 词:糖尿病  动物模型  

Progress in Diabetic Rat Model
CHEN Jiao-li , YANG Ying.Progress in Diabetic Rat Model[J].Journal of Kunming Medical College,2012,33(2):144-146.
Authors:CHEN Jiao-li  YANG Ying
Institution:(Dept.Endocrinology and Metabolism,The 2nd Hospital of Yunnan Province,The 4th Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650021,China)
Abstract:For an in-depth discussion on etiology,pathogenesis and drug treatment of diabetes,the establishment of the ideal diabetic animal model is an important way to undertake a study on diabetes mellitus.Preparation method can be divided into spontaneous diabetes mellitus rat model,induced by experimental models,transgenic and gene knockout models,each with its characteristic.This review will be an update to rat models of type 1 and type 2 diabetes mellitus in these years.
Keywords:Diabetes  Animal mode  Rat
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