临床检验总误差与测量不确定度

在检验医学领域,探讨测量不确定度(measurement uncertainty,MU)和总误差(total error,TE)的区别是个值得关注的问题。多年来,国内外的检验医学专家们对MU进行研究并促进其在检验医学领域的发展,同时也使临床实验室开始关注MU的意义和作用。然而,由于TE在临床实验室中的习惯性使用以及TE与MU二者的概念有类似之处且容易导致混淆,因此许多实验室依然无法完全接受MU。该文通过解释TE与MU的概念,并且分析TE模型与MU模型各自的优缺点和作用,帮助临床实验室进一步了解TE和MU,并在实际工作中合理运用。

Total Error and Measurement Uncertaintyin Clinical Laboratory Medicine

In the clinical laboratory medicine,the measurement uncertainty(MU)is a relatively new concept.Over the years,experts of clinical laboratory medicine from all over the world made a great number of further researches and promote the development of MU, which led clinical laboratoriesto pay more and more attention to the meanings and functions of MU at the sametime.However,because of the habitual using of the total error(TE)in clinicallaboratories and similarities between concepts of MU and TE which easily resulted in confusion,a lot of laboratories still cannot completely accept MU.By explaining concepts of TE and MU and analyzing the pros and cons of models of TE and MU as well as their functions,the objective of this paper is to help clinicallaboratories make further comprehensions of TE and MU and understand how to properly use them in practice.