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| 血小板源性生长因子与后发性白内障的研究进展 | |
| 引用本文： | 刘晓辉,彭燕一. 血小板源性生长因子与后发性白内障的研究进展[J]. 国际眼科杂志, 2011, 11(12): 2128-2130. DOI: 10.3969/j.issn.1672-5123.2011.12.022 |
| 作者姓名： | 刘晓辉 彭燕一 |
| 作者单位： | 桂林医学院附属医院眼科,中国广西壮族自治区桂林市,541001 |
| 摘 要： | 后发性白内障(posterior capsule opacification,PCO)是白内障手术后较为常见的并发症。近年来随着分子生物学及细胞生物学技术的发展,发现生长因子类物质如血小板源性生长因子(platelet-derived growth factor,PDGF)与晶状体上皮细胞的增殖、迁移、纤维分化有密切的关系,对PDGF进行适当的调控可能对于防治PCO有重要意义。我们围绕PDGF对晶状体上皮细胞的作用、PDGF及其受体对PCO形成的影响作简要综述。 |
| 关 键 词： | 血小板源性生长因子 晶状体上皮细胞 增殖 后发性白内障 |
| 收稿时间： | 2011-07-05 |
Platelet-derived growth factor and posterior capsule opacification |
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| Xiao-Hui Liu and Yan-Yi Peng. Platelet-derived growth factor and posterior capsule opacification[J]. International Eye Science, 2011, 11(12): 2128-2130. DOI: 10.3969/j.issn.1672-5123.2011.12.022 | |
| Authors: | Xiao-Hui Liu and Yan-Yi Peng |
| Affiliation: | Department of Ophthalmology,Affiliated Hospital of Guilin Medical University,Guilin 541001,Guangxi Zhuang Autonomous Region,China;Department of Ophthalmology,Affiliated Hospital of Guilin Medical University,Guilin 541001,Guangxi Zhuang Autonomous Region,China |
| Abstract: | Posterior capsule opacification is a more common complication after cataract surgery.In recent years,with the development of molecular biology and cell biology technology,growth factor-type substances such as platelet-derived growth factor(PDGF) are found closely related with proliferation,migration,and differentiation of lens epithelial cell.The appropriate regulation of PDGF may be very important for the prevention of after cataract.This paper focuses on effect of PDGF on lens epithelial cells,effect of PDGF and its receptors on after-cataract formation in a brief review. |
| Keywords: | platelet-derived growth factor lens epithelial cells proliferation posterior capsule opacification |
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