受血者输血前检测 IgA 含量的临床价值

目的：探讨受血者在输血前检测IgA含量的临床应用价值。方法选取300例受血者作为研究对象，并在输血前进行检测IgA含量。结果通过对该组的300例研究对象进行分析，出现5例IgA含量低于正常参考值，IgA缺乏或者低下发生率为1．7％；另外295例IgA含量为正常的参考值，IgA正常率为98.3％。 IgA缺乏或者低下的5例受血者均发生输血超敏反应，发生率为100．0％，IgA含量为正常参考值的295例受血者，出现2例发生输血超敏反应，发生率为0．7％，两者差异有统计学意义（χ2＝7．45，P＜0．05）。结论临床中对于受血者在输血前进行IgA含量的测定，能够有效的指导输血者进行正确输血，有效地降低和预防输血超敏反应情况发生，有效地提高输血安全，在临床中具有重要的应用价值。

The clinical value of detecting the content of IgA in blood recipients before transfusion

Objective To study the clinical application value of detection of IgA content in blood recipients before transfusion .Methods 300 blood recipients were selected as the research subjects ,and the content of IgA was detected before blood transfusion .Results Through the analysis of 300 blood recipients,IgA content of 5 cases was lower than the normal reference value ,the incidence rate of IgA deficiency or low was 1.7%;the IgA content of other 295 cases was in the normal reference value ,the normal rate of IgA was 98.3%.5 blood recipients with IgA deficiency or low were associated with hypersensitivity reactions ,the incidence rate was 100%.Of 295 cases with normal content of IgA,2 cases associated with hypersensitivity reactions ,the incidence rate was 0.7%,the difference between the two groups was statistically significant （χ2 =7.45,P〈0.05）.Conclusion Determination of IgA content in blood recipi-ents before blood transfusion can effectively guide the correct transfusion ,reduce and prevent the occurrence of hyper-sensitivity reactions of transfusion ,improve the safety of blood transfusion ,which has important application value in clinical practice .