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Neuroleptic Malignant Syndrome Associated with Amoxapine and Lithium in an Older Adult
Authors:Sanjay Gupta  Anthony A. Racaniello
Affiliation:(1) Departments of Psychiatry, SUNY Health Science Center at Syracuse, Syracuse, New York; and;(2) School of Medicine and Biomedical Sciences, University of Buffalo, Buffalo, NY;(3) Department of Psychiatry, Olean General Hospital West, 2221 West State Street, Olean, NY, 14760;(4) Genesse County Mental Health Center, Batavia, NY
Abstract:
This report describes the presentation of neuroleptic malignant syndrome (N0M.S) in the primary care setting in an older adult with major depression with psychosis. This patient had been stable on a regimen of amoxapine, lithium carbonate, lorazepam, and benztropine. The patient had rigidity, altered sensorium, diaphoresis, autonomic instability, elevated WBC count and urine myoglobin, and creatine phosphokinase (CPK) reaching 1331 U/I. He was successfully treated with bromocriptine.
Keywords:neuroleptic malignant syndrome  amoxapine
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