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| The Effects of Cyclic Stretching on the Proliferation of Lung Adenocarcinoma Cells in Vitro | |
| 引用本文： | QU Hua1,WU Wen-zhou1,CHEN Wei-yi1 College of Science,Taiyuan University of Technology,Taiyuan 030024,China. The Effects of Cyclic Stretching on the Proliferation of Lung Adenocarcinoma Cells in Vitro[J]. 中国生物医学工程学报(英文版), 2006, 15(1) |
| 作者姓名： | QU Hua1 WU Wen-zhou1 CHEN Wei-yi1 College of Science Taiyuan University of Technology Taiyuan 030024 China |
| 作者单位： | QU Hua1，WU Wen-zhou1，CHEN Wei-yi1 College of Science，Taiyuan University of Technology，Taiyuan 030024，China |
| 基金项目： | 国家自然科学基金;山西省自然科学基金 |
| 摘 要： | Using FX-4000 strain unit, the prolieration in human lung adenocarcinoma A549 cells that underwent mechanical strain of different waveform、frequency and duration were studied. Image analysis revealed that cellular proliferation rate(PR) reduced significantly after cells were subjected to square wave with 0～20% elongation at frequency 30,40,50 and 60 cycles/min for 2h. The PR had no distinct difference at heart wave , triangle wave and sine wave group compared with control. It is concluded that square wave and higher frequency play an important role in inhibiting A549 cells proliferation. |
The Effects of Cyclic Stretching on the Proliferation of Lung Adenocarcinoma Cells in Vitro |
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| QU Hua,WU Wen-zhou,CHEN Wei-yi. The Effects of Cyclic Stretching on the Proliferation of Lung Adenocarcinoma Cells in Vitro[J]. Chinese Journal of Biomedical Engineering, 2006, 15(1) | |
| Authors: | QU Hua WU Wen-zhou CHEN Wei-yi |
| Affiliation: | College of Science, Taiyuan University of Technology, Taiyuan 030024 ,China |
| Abstract: | Using FX-4000 strain unit, the prolieration in human lung adenocarcinoma A549 cells that underwent mechanical strain of different waveform、frequency and duration were studied. Image analysis revealed that cellular proliferation rate(PR) reduced significantly after cells were subjected to square wave with 0～20% elongation at frequency 30,40,50 and 60 cycles/min for 2h. The PR had no distinct difference at heart wave , triangle wave and sine wave group compared with control. It is concluded that square wave and higher frequency play an important role in inhibiting A549 cells proliferation. |
| Keywords: | Cyclic stretch Waveform and frequency Lung adenocarcinoma cell Proliferation rate |
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