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| 硫辛酸联合神经生长因子治疗糖尿病周围神经病变的疗效观察 | |
| 引用本文： | 叶夏云,罗晓红,戴永利. 硫辛酸联合神经生长因子治疗糖尿病周围神经病变的疗效观察[J]. 军医进修学院学报, 2011, 32(12): 1226-1227,1276 |
| 作者姓名： | 叶夏云 罗晓红 戴永利 |
| 作者单位： | 兰州军区兰州总医院内分泌科,兰州,730050 |
| 基金项目： | 军队医药卫生科研基金资助课题(CWS10JA18)~~ |
| 摘 要： | 目的 研究硫辛酸联合神经生长因子治疗糖尿病周围神经病变的疗效.方法 将96例糖尿病周围神经病变患者随机分为实验组50例及对照组46例,两组均予以常规治疗,实验组在此基础上加用硫辛酸和神经生长因子,4周后比较两组的临床疗效及神经传导速度改善情况.结果 两组临床症状和神经传导速度均有所改善,实验组显效率和神经传导速度增加幅度显著高于对照组(P＜0.05).结论 硫辛酸联合神经生长因子治疗糖尿病周围神经病变疗效显著. |
| 关 键 词： | 糖尿病周围神经病变 硫辛酸 神经生长因子 |
Effect of ipoic acid and nerve growth factor on diabetic peripheral neuropathy |
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| YE Xia-yun , LUO Xiao-hong , DAI Yong-li. Effect of ipoic acid and nerve growth factor on diabetic peripheral neuropathy[J]. Academic Journal of Pla Postgraduate Medical School, 2011, 32(12): 1226-1227,1276 | |
| Authors: | YE Xia-yun LUO Xiao-hong DAI Yong-li |
| Affiliation: | Department of Endocrinology,General Hospital of Lanzhou Military Area Command,Lanzhou 730050,Gansu Province,China |
| Abstract: | Objective To study the effect of ipoic acid and nerve growth factor on diabetic peripheral neuropathy（DPN）.Methods Ninety-six patients with DPN were divided into experimental group（n=50） and control group（n=46）.Patients in control group received routine therapy,and those in experimental group received routine therapy plus ipoic acid and nerve growth factor.Clinical therapeutic effect and nerve conduction velocity were compared between the two groups 4 weeks after treatment.Results The clinical symptoms and nerve conduction velocity were significantly improved in both groups after treatment.The improvement in clinical therapeutic effect and nerve conduction velocity was significantly better in experimental group than in control group（P〈0.05）.Conclusion The therapeutic effect of combined ipoic acid and nerve growth factor is rather good for DPN. |
| Keywords: | diabetic peripheral neuropathy thioctic acid nerve growth factor |
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