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维胺酯-β-环糊精包合物的研究
引用本文:孙淑英 张晓菁. 维胺酯-β-环糊精包合物的研究[J]. 沈阳药科大学学报, 1997, 14(3): 157-160
作者姓名:孙淑英 张晓菁
作者单位:沈阳药科大学药学系,沈阳志鹰制药厂
摘    要:应用3因素8水平的均匀设计方法,优化出维胺酯-β-环糊精包合物最佳制备条件,所得包合物的包合率为99.3%,其表观稳定常数为1394M-1.

关 键 词:维胺酯;β-环糊精;包合物;均匀设计

Study on Retinamido Ester β Cyclodextrin Inclusion Complexes
Sun Shuying,Zhang Xiaoqing,Yang Huaping,Liu Xiulan,Zhang Jinsong. Study on Retinamido Ester β Cyclodextrin Inclusion Complexes[J]. Journal of Shenyang Pharmaceutical University, 1997, 14(3): 157-160
Authors:Sun Shuying  Zhang Xiaoqing  Yang Huaping  Liu Xiulan  Zhang Jinsong
Abstract:In this study 3 factors and 8 levels of conditions for the preparation of the retinamido ester β CD inclusion complex were selected by the uniform design.An optimal condition was established.Under the optimal conditions the inclusion complex was prepared.The drug,including rate was 99 3%.The apparently stability constant of the inclusion complex was 1294 M -1 .
Keywords:retinamido ester  β cyclodextrin  inclusion complex  uniform design
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