白血病患儿的生存质量及其影响因素调查

目的:调查白血病患儿的生存质量(QOL),探讨影响其QOL的相关因素。方法:选择2006年1月～2011年5月接受治疗的白血病患儿364例,同时配对选取364例健康儿童作为对照组,采用自拟的调查问卷和生存质量普适性核心量表(PedsQL4.0)对两组儿童的生存质量进行调查,分析相关因素对白血病患儿的生存质量的影响。结果:白血病患儿生理功能、社会功能、角色功能以及情感功能等4个维度生命质量评分分别为(51.99±19.04)分、(65.30±17.37)分、(21.57±28.28)分和(59.61±15.42)分,生命质量平均评分为(50.07±14.06)分,显著低于正常儿童(P<0.01);患儿年龄、病情、家属文化程度、家庭收入、患儿住院次数和天数、社会帮助程度和频率与白血病患儿的4个维度生命质量评分有统计学相关性(P<0.05)。结论:白血病患儿的生存质量明显低于正常儿童,患儿年龄、患病程度、家属文化程度、家庭收入、患儿住院次数和天数以及社会帮助等因素会影响患儿生存质量。

Investigation on quality of life of children with leukemia and the influencing factors

Objective:To investigate the quality of life(QOL) of children with leukemia,and explore the related influencing factors.Methods:A total of 364 children with leukemia who were treated in the hospital from January 2006 to May 2011 were selected,and 364 healthy children were selected as control group;a self-designed questionnaire and PedsQL4.0 were used to investigate QOLs of children in the two groups,the effects of related factors on QOL of children with leukemia were analyzed.Results:The scores of QOL of physiological function,social function,role function,and emotional function in children with leukemia were(51.99±19.04),(65.30±17.37),(21.57±28.28),and(59.61±15.42),respectively;the mean score of QOL was(50.07±14.06),which was statistically significantly lower than that in control group(P<0.01).There was a positive correlation between age,patient' s condition,educational levels of family members,family income,times and duration time of hospitalization,degree and frequency of social support and scores of QOL of four dimensions(P<0.05).Conclusion:QOL of children with leukemia is significantly lower than that of normal children;age,patient's condition,educational levels of family members,family income,times and duration time of hospitalization,degree and frequency of social support have impacts on QOL of the children with leukemia.