结核分枝杆菌实验室检测方法的研究进展

结核病是由结核分枝杆菌引起的传染病。它已成为严重危害人民身体健康、发病率及病死率很高的传染病。由于细菌学检查阳性率低及血清学诊断的敏感性和特异性不高等原因,因此结核病的诊断一直是临床上的难题。发现和研究对结核分枝杆菌诊断较敏感和特异性且快速、简便的实验室检测方法,对结核病的预防和诊断具有重要的意义。笔者就目前国内外结核分枝杆菌的检测方法现状及其进展作一综述。

Research progress of laboratory testing methods for mycobacterium tuberculosis

Tuberculosis caused by mycobacterium tuberculosis has become an infectious disease with features of severely damaging people＇s health, high incidence rate and high fatality rate. Due to low positive rate by bacteriologic test, and little sensitivity and specificity in serodiagnosis, the tuberculosis diagnosis has always been a problem in clinic. To detect and study a fast and simple laboratory testing method with high sensitivity and specificity for mycobacterium tuberculosis plays an important significance in the prevention and diagnosis of tuberculosis. The article is going to review the current situations and progresses of testing methods for mycobacterium tuberculosis both home and abroad.