非酒精性脂肪肝的多囊卵巢综合征患者的临床资料分析

目的:探讨伴非酒精性脂肪肝的多囊卵巢综合征患者的临床症状及相关指标。方法:收集50例非酒精性脂肪肝的多囊卵巢综合征患者的临床资料(观察组);同时收集无非酒精性脂肪肝的50例PCOS患者的临床资料(对照组)。比较两组患者的体征、生殖激素、血糖血脂代谢等相关指标。结果:观察组患者的平均BMI、WHR、FINS、HOMA-IR、TC、TG、T高于对照组,HDL-C低于对照组(P<0.05);WHR、TG、HOMA-IR可能是导致PCOS患者并发NAFLD的独立危险因素(P<0.05)。结论:合并NAFLD的PCOS患者多伴有肥胖、血糖血脂代谢异常及T水平偏高,该类PCOS患者需预防非酒精性脂肪肝的发生。

Analysis on clinical data of patients with polycystic ovary syndrome and non-alcoholic fatty liver disease

Objective:To explore the clinical symptoms and related indexes of patients with polycystic ovary syndrome(PCOS) and non-alcoholic fatty liver disease.Methods:The clinical data of 50 patients with PCOS and non-alcoholic fatty liver disease(observation group) were collected,and the clinical data of 50 PCOS patients without non-alcoholic fatty liver disease(control group) were collected during the same period.The signs,sex hormones levels,related indexes of blood glucose metabolism and blood lipid metabolism in the two groups were compared.Results:The mean body mass index(BMI),waist hip rate(WHR),fasting insulin,homeostasis model assessment of insulin resistance(HOMA-IR),total cholesterol(TC),total glycerin(TG),and testosterone levels in observation group were statistically significantly higher than those in control group,while high-density lipoprotein cholesterol(HDL-C) level in observation group was statistically significantly lower than that in control group(P<0.05);WHR,TG,and HOMA-IR were independent risk factors of PCOS combined with non-alcoholic fatty liver disease(P<0.05).Conclusion:Most PCOS patients with non-alcoholic fatty liver disease are combined with obesity,abnormal blood glucose metabolism and blood lipid metabolism,and increase of testosterone level;for the patients,non-alcoholic fatty liver disease should be prevented.