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Isoindolinone inhibitors of the murine double minute 2 (MDM2)-p53 protein-protein interaction: structure-activity studies leading to improved potency
Authors:Hardcastle Ian R  Liu Junfeng  Valeur Eric  Watson Anna  Ahmed Shafiq U  Blackburn Timothy J  Bennaceur Karim  Clegg William  Drummond Catherine  Endicott Jane A  Golding Bernard T  Griffin Roger J  Gruber Jan  Haggerty Karen  Harrington Ross W  Hutton Claire  Kemp Stuart  Lu Xiaohong  McDonnell James M  Newell David R  Noble Martin E M  Payne Sara L  Revill Charlotte H  Riedinger Christiane  Xu Qing  Lunec John
Affiliation:Newcastle Cancer Centre, Northern Institute for Cancer Research and School of Chemistry, Bedson Building, Newcastle University, Newcastle NE1 7RU, United Kingdom. i.r.hardcastle@ncl.ac.uk
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