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Intra-arterial thrombolysis for acute ischemic stroke
Authors:W. C. Burnette  G. M. Nesbit
Affiliation:(1) Department of Diagnostic Radiology, Oregon Health Sciences University, Portland, Oregon 97201–3098, USA, US;(2) Department of Diagnostic Radiology, Neurological Surgery and the Dotter Interventional Institute, Oregon Health Sciences University, Portland, Oregon 97201–3098, USA, US
Abstract:
Intra-arterial thrombolysis is a maturing treatment for acute thromboembolic stroke that shows promise in restoring cerebral blood supply. Reviewed evidence suggests that intra-arterial treatment has a longer window for treatment than intravenous t-PA and does improve outcome. A favorable outcome is dependent on careful patient selection aimed at avoiding intracranial hemorrhage. This article describes features to evaluate for patient selection and highlights factors along the treatment algorithm to maximize success. Received: 19 June 2000 Accepted: 10 July 2000
Keywords:Cerebrovascular accident  Drug therapy  Fibrinolytic agents  Intra-arterial infusions  Thrombolytic therapy
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