Sinus arrest with intravenous amiodarone

Amiodarone is a benzofuran derivative with potent electrophysiologic effects on the impulse generation and conduction system of the heart.¹ The effects of amiodarone on the sinus node, in particular, are well described.^2,3 Sinus arrest⁴ and sinoatrial block(5) with oral therapy have been demonstrated; we describe a patient with acute sinus arrest after intravenous amiodarone therapy.