骨髓转移瘤的病理组织学与临床特点

目的：研究骨髓转移瘤的临床和病理学特点。方法：骨髓活检塑料包埋切片，Ｈ－Ｇｍｉｅｓａ－Ｅ，Ｇｏｍｏｒｉ，ＰＡＳ，Ａｌｃｉｎ ｂｌｕｅ染色。结果：６６例骨髓转移瘤中，低分化腺癌４２例、黏液腺癌６例、黏液细胞癌３例、代分化鳞癌９例、巨细胞癌２例、未分化癌２例、恶性黑色素瘤１例、恶性纤维组织细胞瘤１例。临床表现以贫血最常见（９５，１％），其次为血小板减少（５９．５％）和骨髓（５７．４％）。临床初诊常误诊

Clinicohistopathologic features of metastatic tumor in bone marrow

Objective:To study clinicohistopathologic features of bone marrow metastatic tumor(BMMT).Methods:Bone marrow biopsy plastic embedded section stained by H Giemsa E,PAS and Alcin blue.Results:Among 66 BMMTs were 42 poorly differentiated adenocarcinomas,6 mucinous adenocarcinomas,3 mucinous carcinomas,9 poorly differentiated squamous cell carcinomas,2 jiant cell carcinomas,2 undfferentiated carcinomas,and 1 melanoma and malignant fibrohistocytoma respectively.Anemia was mostly frequent clinical menifestation of BMMT,the secondary was thrombocytopenia( 59.5 %)and bone pain( 57.4 %).Multipl myeloma or other blood diseases were easily misdiagnosed .49( 74.2 %) primary tumor site were not found at present.Clinicopathologic features of BMMT ( 95.1 %) were discussed.Conclusion:Bone marrow biopsy is important for BMMT when primary tumor site is unknow.