超敏C反应蛋白和D-二聚体联合检测在脑梗死中的应用

目的：研究超敏C反应蛋白和D-二聚体在脑梗死患者中的变化及临床意义。方法选取135例脑梗死患者和60例体检健康人，采用免疫比浊法分别检测血浆中C反应蛋白和D-二聚体含量。结果脑梗死组血浆C反应蛋白和D-二聚体含量明显高于健康对照组（P＜0.05），脑梗死组神经功能缺损越严重，其血浆中C反应蛋白和D-二聚体含量就越高（P＜0.05或P＜0.01）。经治疗后，缓解组血浆中C反应蛋白和D-二聚体含量较未缓解组低（P＜0.01），未缓解组血浆中C反应蛋白和D-二聚体含量较未缓解组变化不大（P＞0.05）。结论 C反应蛋白和D-二聚体联合检测在脑梗死的诊断具有重要意义，并且可用于观察治疗效果。

Applications of High-sensitivity C-reactive Protein and D-dimer Combined Detection of Cerebral Infarction

Objective To study the high sensitive C reactive protein and D two poly change in patients with cerebral infarction and its clinical signiifcance. Methods 135 patients with cerebral infarction and 60 healthy people, by immune turbidimetry respectively to detect plasma C reactive protein and D two dimer content. Results Incidence of plasma C reactive protein and D two dimer content was obviously higher than that in the healthy control group （P〈0.05）, nerve function of cerebral infarction is more serious, the levels of C reactive protein and D two dimer content is higher （P〈0.05 or P〈0.01）. After the treatment, the remission group in plasma C reactive protein and D two dimer content is no remission group （P〈0.01）, non remission group. Plasma C reactive protein and D two dimer content is no remission group changed little （P〉0.05）. Conclusion C reactive protein and two D dimer detection in the diagnosis of cerebral infarction fault is of great signiifcance, and can be used to observe the therapeutic effect.