超声造影技术对子宫内膜癌肌层浸润深度诊断价值的探讨

目的探讨超声造影技术对子宫内膜癌肌层浸润深度的诊断价值。方法对我院自2005年6月至2007年12月期间经诊刮确诊为子宫内膜癌患者,行超声造影检查,选择手术病理分期为I期的30例患者为研究对象,进行回顾性分析。将术前超声造影检查及术中肉眼观察的内膜癌肌层浸润情况,与术后的病理诊断相比较。结果30例患者中,病理检查诊断为Ⅰa期5例,Ⅰb期19例,Ⅰc期6例。术前超声造影检查的总符合率为66.7%(20/30)。经一致性检验,Kappa=0.435,提示超声造影检查与病理结果之间存在中等程度的一致性。术中肉眼观察的总符合率为56.7%(17/30),经一致性检验,Kappa=0.287,提示两者一致性属一般。术前超声造影检查判断肌层浸润的敏感性、特异性、准确率、阳性预测值和阴性预测值分别为84.0%、2/5、76.7%、87.5%和2/6;术中肉眼观察分别为76.0%、3/5、73.3%、90.5%、3/9。术前超声造影判断深肌层浸润的敏感性、特异性、准确率、阳性预测值和阴性预测值分别为5/6、87.5%、86.7%、5/8和95.5%;术中肉眼观察分别为4/6、87.7%、83.3%、4/7、91.3%。结论术前应用超声造影辅助诊断内膜癌的肌层浸润深度有一定意义,优于术中肉眼观察,但对于合并子宫肌腺症及病灶较大的患者易误诊,需扩大样本量及积累操作经验进一步评价其意义。

Contrast-enhanced ultrasound in the evaluation of myometrial invasion in endometrial carcinoma

Objectives: To examine the value of preoperative contrast-enhanced ultrasound in evaluating myometrial invasion in endometrial carcinoma.Methods: A total of 30 women with grade I endometrial carcinoma that were confirmed by postoperative pathology were retrospectively analyzed,with the focus on the evaluation of the diagnosis of myometrial invasion by preoperative contrast-enhanced ultrasound,intraoperative gross visual inspection and postoperative pathological staging.Results: In the diagnosis of myometria...