两种手术方式治疗复发性翼状胬肉伴睑球粘连的疗效对比

目的:角膜缘干细胞移植与羊膜移植治疗复发性翼状胬肉伴睑球粘连的疗效分析。方法:复发性翼状胬肉伴睑球粘连患者80例。按照随机方式分为翼状胬肉切除术联合角膜缘干细胞移植、翼状胬肉切除联合羊膜移植组,每组40例。术后随访6mo,观察翼状胬肉及睑球粘连的复发率。结果:角膜缘干细胞移植组有2例复发(5%),羊膜移植组有8例复发(20%),两组比较有统计学意义(P<0.05)。结论:两种术式均能显著降低复发性翼状胬肉术后复发率,但角膜缘干细胞移植术后复发率更低。

Comparation on effect of two kinds operation in treatment of recurrent pterygium with symblepharon

AIM: To analyze the effect of corneal limbus stem cell transplantation and amniotic membrane transplantation in treatment of recurrent pterygium with symblepharon.

METHODS:Totally 80 cases of patients with recurrent pterygium and symblepharon were randomly divided into pterygium resection combined with limbal stem cell transplantation group and pterygium excision with amniotic membrane transplantation group, 40 cases in each group. All patients were followed up for 6mo after the operation, the recurrence rate of pterygium and symblepharon were observed.

RESULTS:There were 2 cases of recurrence in the group of corneal limbus stem cell transplantation(5%), 8 cases of recurrence in the group of amniotic membrane transplantation(20%), with statistical difference between two groups(P<0.05).

CONCLUSION:Two kinds operation could significantly reduce the recurrence rate of recurrent pterygium, but the corneal limbus stem cell transplantation group has the lower recurrence rate.