左卡尼汀联合稳心颗粒治疗不稳定型心绞痛45例

目的 探讨左卡尼汀联合稳心颗粒治疗不稳定型心绞痛（UAP）的效果。方法 90例UAP患者按入院先后顺序随机分为观察组和对照组,每组45例。两组患者均给予西医常规治疗,观察组在此基础上加用左卡尼汀和稳心颗粒。结果 观察组总有效率为95.56%（43/45）,对照组为77.78%（35/45）,差异有统计学意义（χ2=6.15,P〈0.05）。两组治疗后心绞痛积分及高敏C反应蛋白（hs-CRP）均显著降低（P〈0.05）,且观察组显著低于对照组（P〈0.05）。两组均未见明显不良反应。结论 左卡尼汀联合稳心颗粒能有效改善UAP症状,标本同治兼顾,安全指数高,值得临床推广。

Observation on Effect of L- Carnitine Combined with Wenxin Granules in Treating 45 Cases of Unstable Angina Pectoris

Objective To investigate the effect of L-carnitine combined with Wenxin Granules in treating unstable angina pectoris （UAP）. Methods 90 cases of UAP were randomly divided into the observation and the control group according to the order of hospital admission,45 cases in each group. Both of the two groups were given the Western medicine routine treatment,on this basis the observation group was added with L- carnitine and Wenxin Granules. Results The total effective rate of the observation group was 95.56% （43/45） and which of the control group was 77.78% （35/45）% ,the difference was statistically significant （X2 =6. 15, P 〈 0.05）. After treatment,the angina scores and hs- CRP in the two groups were significantly decreased （P 〈 0. 05 ） , moreover the observation group was significantly lower than the control group（ P 〈 0.05）. No obvious adverse reactions occurred in the two groups. Conclusion L- carnitine combined with Wenxin Granules can effectively improve the symptoms of UAP with high security index and is worthy of clinical promotion and application.