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Postexposure rabies prophylaxis in an urban emergency department
Affiliation:1. Service de chirurgie maxillofaciale et chirurgie plastique, Hôpital Necker – Enfants Malades, Assistance Publique – Hôpitaux de Paris, Faculté de Médecine, Université de Paris, 149 rue de Sèvres, Paris 75015, France;2. AP-HP.Centre, Groupe Hospitalier Cochin Port Royal, DMU PRIME, Unité de Recherche Clinique, Paris, France;3. Service des urgences pédiatriques, Hôpital Necker – Enfants Malades, Assistance Publique – Hôpitaux de Paris; Faculté de Médecine, Université de Paris, Paris, France;4. Service d''anesthésie-réanimation pédiatrique et obstétricale, Hôpital universitaire Necker – Enfants Malades, Assistance Publique – Hôpitaux de Paris; Faculté de Médecine, Université de Paris & EA 7323, Pharmacologie et évaluation des thérapeutiques chez l''enfant et la femme enceinte, Université de Paris, Paris, France;5. Services des urgences pédiatriques, Hôpital Robert-Debré, Assistance Publique – Hôpitaux de Paris ; Faculté de Médecine, Université de Paris, Paris, France;6. Service social, Hôpital Necker – Enfants Malades, Assistance Publique – Hôpitaux de Paris; Faculté de Médecine, Université de Paris, Paris, France
Abstract:
The purpose of this retrospective study was to identify those patients presenting to an urban emergency department with animal-related wounds, define source animal demographics, and assess adequacy of wound care, rabies immunoprophylaxis, and follow-up. Sixty-three patients comprised the study population; dogs (76%) and cats (16%) were the principal source animals. Postexposure rabies prophylaxis was indicated in ten patients (16%) due to wounds inflicted by stray dogs and cats. Animal behavior and vaccination history were inconsistently addressed, but were documented significantly more often in patients who received prophylaxis. Inclusion of soap in wound care was not significantly more common in the treated group. Human rabies immune globulin was administered incorrectly at least one-third of the time. Appropriate follow-up was arranged in only 31% of cases; this occurred significantly more offen with treated patients. An awareness of both regional epidemiological trends in animal rabies and local health department treatment recommendations will encourage optimal delivery of postexposure treatment in cases of potential rabies exposure.
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