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| 滋阴清肝消痤汤治疗寻常痤疮48例临床与实验研究 | |
| 引用本文： | 刘靖,邝枣园,陈妙欢,罗海燕,范瑞强.滋阴清肝消痤汤治疗寻常痤疮48例临床与实验研究[J].中医杂志,2005,46(8):605-607. |
| 作者姓名： | 刘靖 邝枣园 陈妙欢 罗海燕 范瑞强 |
| 作者单位： | 1. 广州中医药大学第一附属医院皮肤科,广东省广州市机场路16号,510405 2. 广州中医药大学微生物学实验室 3. 广东省中医院皮肤科 |
| 摘 要： | 目的:研究滋阴清肝消痤汤治疗寻常痤疮的临床疗效及作用机理.方法:采用随机对照法对80例寻常痤疮进行临床疗效观察,治疗前后分别测定治疗组(滋阴清肝消痤汤组)和对照组(四环素组)患者血清睾酮、雌二醇水平,并进行体外抗菌试验.结果:治疗组48例,总有效率85.42%,对照组32例,总有效率84.38%,两组疗效差异无显著性(P>0.05).滋阴清肝消痤汤对痤疮丙酸杆菌的最小抑菌浓度(MIC)是0.0125g/ml,对金黄色葡萄球菌的MIC是0.025g/m1.结论:该方具有明显的抗雄激素活性及温和的雌激素活性,有调节内分泌及杀菌抗炎的作用. |
| 关 键 词： | 痤疮 寻常/中医药疗法 @滋阴清肝消痤汤 |
| 收稿时间： | 11 2 2004 12:00AM |
| 修稿时间： | 2004-11-022004-12-25 |
Clinical and Experimental Study on Ziyin Qinggan Xiaocuo Decoction for Treatment of 48 Cases of Acne Vulgaris |
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| Liu Jing;Kuang ZaoYuan;Chen MiaoHuan;Luo HaiYan;Fan RuiJiang.Clinical and Experimental Study on Ziyin Qinggan Xiaocuo Decoction for Treatment of 48 Cases of Acne Vulgaris[J].Journal of Traditional Chinese Medicine,2005,46(8):605-607. | |
| Authors: | Liu Jing;Kuang ZaoYuan;Chen MiaoHuan;Luo HaiYan;Fan RuiJiang |
| Abstract: | Objective To study on clinical therapeutic effect and the mechanism of Ziyin Qinggan Xiaocuo Decoction for treatment of ache vulgaris.Methods:80 cases of acne vulgaris were randomly divided into a treatment group(Ziyin Qinggan Xiaocuo Decoction group,18 cases)and a control group(tetracycline group,32 cases),and serum testosterone(T)and estradiol(E_2)level before and after treatmcnt were determined and the antibacterial test in vitro was carried out.Results:The total effective rate was 85.42% in tbe treatment group and 81.38% in the control group with no significant difference between the two groups(P>0.05).Minimal inhibiting bacteria content(MIC)of Ziyin Qinggan Xiaocuo Decoction for acne propionic bacillus was 12.5mg/ml and for Staphylococcus Aureus was 25.0mg/ml.Conclusion:This recipe is of obvious anti-androgen and mild estrogen activities. |
| Keywords: | Acne vulgaris/TCM therapy @ Ziyin Qinggan Xiaocuo Decoction |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |