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| 还原型谷胱甘肽治疗肝病的评估 | |
| 引用本文： | 范付萍,曾民德,巫善明,邬祥惠,周霞秋,蔡伊梅,陈成伟,王国傻,蔡雄,潘钰卿,胡德昌,王秀玲,泰一中,戴兆云,杨广顺,韩少成. 还原型谷胱甘肽治疗肝病的评估[J]. 胃肠病学, 1999, 4(2): 89-92 |
| 作者姓名： | 范付萍 曾民德 巫善明 邬祥惠 周霞秋 蔡伊梅 陈成伟 王国傻 蔡雄 潘钰卿 胡德昌 王秀玲 泰一中 戴兆云 杨广顺 韩少成 |
| 作者单位： | 上海第二医科大学附属仁济医院消化科!200001，上海第二医科大学附属仁济医院消化科!200001，上海市传染病医院!200083，上海医科大学附属华山医院传染科!200040，上海第二医科大学附属瑞金医院传染科!200025，上海第二医科大学附属瑞金医院传染科!200025，中国人民解放军第85医院!20 |
| 摘 要： | 目的：探讨还原型谷胱甘肽治疗肝病的疗效和安全性。方法：２９５例肝病病人，男性２２９例，女性６６例，年龄（４４±１２ 岁）。用谷胱甘肽注射液１２００ｍｇ加入５％葡萄糖液２５０ｍｌ中静滴，ｑｄ × ３ｗｋ为一个疗程（用１～３个疗程）。结果：治疗前 ＡＬＴ、ＡＳＴ、ＳＢ、ＴＧ、ＬＤＬ分别为２６０ＩＵ／Ｌ±３７５ＩＵ／Ｌ、２０６ＩＵ／Ｌ±３６０ＩＵ／Ｌ、１３２μｍｏｌ／Ｌ±１５９μｍｏｌ／Ｌ、３.０μｍｏｌ／Ｌ ±１．５ｍｍｏｌ／Ｌ和３．２ｍｍｏｌ／Ｌ±０．８ｍｍｏｌ／Ｌ。治疗３ｗｂ后依次为７３ＩＵ／Ｌ±７４ＩＵ／Ｌ、７６ＩＵ／Ｌ±８９ＩＵ／Ｌ、１０７μｍｏｌ／Ｌ± １６１μｍｏｌ／Ｌ、２．７ｍｍｏｌ／Ｌ±１．４ｍｍｏｌ／Ｌ、２．９ｍｍｏｌ／Ｌ±１．８ｍｍｏｌ／Ｌ。３ｗｋ时总有效率为７７．８％。６ｗｋ时８４．３％，９ｗｋ时 为８９．３％。不良反应轻微。结论：还原型谷胱甘肽是一安全有效的保肝药物。 |
| 关 键 词： | 治疗前 肝病 还原型谷胱甘肽 5％葡萄糖 总有效率 保肝药物 静滴 结论 方法 AST |
Reduced Glutathione in the Treatment of Liver Disease: Clinical Analysis of 295 Cases |
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| Fan Zhu-Ping,Zeng Min-de,Wu Shan-ming,et al.. Reduced Glutathione in the Treatment of Liver Disease: Clinical Analysis of 295 Cases[J]. Chinese Journal of Gastroenterology, 1999, 4(2): 89-92 | |
| Authors: | Fan Zhu-Ping Zeng Min-de Wu Shan-ming et al. |
| Abstract: | Background/Aims: To discuss the efficacy and safety of reduced glutathione in the treatment of liver diseases. Methods: 295 cases of liver diseases (male: 229, female: 66) with elevated level of serum ALT and SB received TAD treatment (1200mg/day) for three weeks. In 295 cases there were 126 cases of chronic hepatitis B, 61 severe chronic hepatitis; 17 drug induced liver diseases, 50 active liver cirrhosis, 10 fatty liver, and 31 liver damage of post-operation and chemotherapy. Results: The rates of clinical efficacy were 77.8% and 84.3%, respectively, after three weeks and six weeks treatment. Conclusions: Reduced glutathione is effective and safe in the treatment of liver diseases. |
| Keywords: | Reduced glutathione Liver disease Liver function test |
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