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Evolution of portal vein tumor thromboses in patients with hepatocellular carcinoma: CT findings and transition of serum tumor markers
Authors:Il Soo Chang  Sung Wook Shin  Sung Ki Cho  Hyunchul Rhim  Dongil Choi  Kwang Bo Park  Hong Suk Park  Sung Wook Choo  Young Soo Do  In-Wook Choo
Affiliation:Department of Radiology and Research Institute of Biomedical Science, Konkuk University School of Medicine, Seoul, Republic of Korea.
Abstract:We investigated the patterns of evolution of portal vein tumor thromboses (PVTTs) and the changes in serum tumor marker levels in untreated hepatocellular carcinomas. The mean time required for the subsegmental or lower-order branch PVTTs and the segmental PVTTs to reach the large portal vein was 120 and 101 days, respectively. The mean values of the serum alpha-fetoprotein levels markedly increased after the appearance of PVTTs from 1858.7 ng/ml to 6795.2 ng/ml.
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