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| 南京大学医学院附属鼓楼医院2010年698例药品不良反应回顾性分析 | |
| 引用本文： | 徐红,徐丽华. 南京大学医学院附属鼓楼医院2010年698例药品不良反应回顾性分析[J]. 药学服务与研究, 2011, 11(6): 459-461 |
| 作者姓名： | 徐红 徐丽华 |
| 作者单位： | 南京大学医学院附属鼓楼医院药剂科,南京,210008 |
| 摘 要： | 目的:分析药品不良反应(ADRs)发生的情况和原因,制定防范措施。方法:运用Excel软件对南京大学医学院附属鼓楼医院698例ADRs报告分类统计分析,计算ADRs发生例数、ADRs例数与其用药频度(DDDs)的比值(相对发生率)。结果:抗感染药引起的ADRs为264例(37.82%),其中左氧氟沙星73例居首位,其次为循环系统药113例(16.19%)和抗肿瘤药92例(13.18%)。用药频度(DDDs)则抗感染药中的左氧氟沙星排序第一,ADRs例数/DDDs比值排序的均值抗肿瘤药为8.5,排序第一。ADRs的临床表现以皮肤及附件损害最为常见,共255例(36.53%)。结论:须进一步加强ADRs的监测,并做好相应的防范措施,减少或避免ADRs发生。 |
| 关 键 词： | 药物副反应报告系统 用药频度 药学服务 |
Retrospective analysis of 698 case reports of adverse drug reactions in 2010 of Drum Tower Hospital affiliated to School of Medicine,Nanjing University |
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| XU Hong , XU LiHua. Retrospective analysis of 698 case reports of adverse drug reactions in 2010 of Drum Tower Hospital affiliated to School of Medicine,Nanjing University[J]. Pharmaceutical Care and Research, 2011, 11(6): 459-461 | |
| Authors: | XU Hong XU LiHua |
| Affiliation: | XU Hong,XU LiHua(Department of Pharmacy,Drum Tower Hospital affiliated to School of Medicine,Nanjing University,Nanjing 210008,China) |
| Abstract: | Objective: To analyze the status and reasons of adverse drug reactions(ADRs) in Drum Tower Hospital affiliated to School of Medicine,Nanjing University,and make precautions.Methods:Six hundred and ninety-eight reports of ADRs were analyzed retrospectively by Excel software.The numbers of ADRs,the ratios of numbers of ADRs and DDDs were calculated.Results:The numbers of ADRs induced by anti-infection drugs was 264 cases(37.82%),among which,levofloxacin(73 cases) ranked the first,followed by circulatory syste... |
| Keywords: | adverse drug reaction reporting systems DDDs pharmaceutical care |
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