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| 急性ST段抬高心肌梗死急诊介入治疗中冠脉内注射替罗非班对TIMI血流和临床预后的影响 | |
| 引用本文： | 王鹏飞,金卫东,邢永生,侯永兰. 急性ST段抬高心肌梗死急诊介入治疗中冠脉内注射替罗非班对TIMI血流和临床预后的影响[J]. 中国实用医药, 2011, 6(8): 11-13 |
| 作者姓名： | 王鹏飞 金卫东 邢永生 侯永兰 |
| 作者单位： | 河南省新乡市中心医院心内一科,453000 |
| 摘 要： | 目的 观察急性ST段抬高心肌梗死(STEMI)患者急诊经皮冠状动脉介入治疗(PCI)术中冠脉内直接注射替罗非班的临床效果和安全性.方法 符合急性STEMI入选标准的患者112例,随机分为静脉组和冠脉组.静脉组静脉推注后持续泵入,冠脉组冠脉内推注后持续泵入.观察两组冠脉造影资料、PCI术开始时和结束时的冠脉TIMI血流分级、不良心脏事件、出血等并发症.结果 与静脉组相比,冠脉组PCI后TIMI血流分级和血栓情况改善明显(P<0.05);14 d的心功能、主要心脏不良事件、出血等无差别.结论 对急性STEMI患者,急诊PCI术中冠脉内应用替罗非班安全有效. |
| 关 键 词： | 替罗非班 急性心肌梗死 冠状动脉介入治疗 |
Clinical Application of Intra Coronary Administration of Tirofiban in Patients With Acute Myocardial Infarction During Percutaneous Intervention |
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| WANG Peng-fei,JIN Wei-dong,XING Yong-sheng,et al.. Clinical Application of Intra Coronary Administration of Tirofiban in Patients With Acute Myocardial Infarction During Percutaneous Intervention[J]. China Practical Medical, 2011, 6(8): 11-13 | |
| Authors: | WANG Peng-fei JIN Wei-dong XING Yong-sheng et al. |
| Affiliation: | WANG Peng-fei,JIN Wei-dong,XING Yong-sheng,et al. Cardiovascular Dept of center Hospital,Xinxiang,Henan 453000,China |
| Abstract: | Objective To evaluate the efficacy and safety of intracoronary administration of tirofiban on TIMI bleeding in percutaneous coronary intervention (PCI) patients with acute myocardial infarction (AMI). Methods 112 patients with AMI were randomized into two groups given tirofiban IV or IA. The efficacy of therapy, the adverse events(death, myocardial infarction, or urgent revascularizations)and major bleeding events were recorded after 30 days of follow-up. Results Normal TIMI myocardial perfusion grade 3 flo... |
| Keywords: | Tirofiban acute myocardial infarction Percutaneous coronary intervention |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |