| 齐拉西酮与氯氮平治疗精神分裂症对照研究 |
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| 引用本文： | 庞良俊,杨琪,谢思思,朱道明. 齐拉西酮与氯氮平治疗精神分裂症对照研究[J]. 临床精神医学杂志, 2010, 20(2): 119-120 |
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| 作者姓名： | 庞良俊 杨琪 谢思思 朱道明 |
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| 作者单位： | 合肥市第四人民医院,230022 |
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| 摘 要： | 目的：探讨齐拉西酮治疗精神分裂症的疗效和不良反应。方法：将60例符合中国精神障碍分类与诊断标准第3版的精神分裂症患者，随机分为齐拉西酮组和氯氮平组，疗程6周，用阳性与阴性症状量表（PANSS）评定疗效，用治疗中出现的症状量表（TESS）观察不良反应，分别于治疗前、治疗2周、治疗4周评定1次一结果：两组疗效差异无显著性（P〉0．05），齐拉西酮不良反应显著少于氯氮平。结论：齐拉西酮对精冲分裂症的疗效与氯氮平相当，不良反应较小，服药依从好，可作为分裂症的首选药物。
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| 关 键 词： | 齐拉西酮 氯氮平 精神分裂症 |
A comparative study of ziprasidone and clozapine in treatment of schizophrenia |
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| PANG Liang-jun,YANG Qi,XIE Si-si,ZHU Dao-ming. A comparative study of ziprasidone and clozapine in treatment of schizophrenia[J]. Journal of Clinical Psychological Medicine, 2010, 20(2): 119-120 |
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| Authors: | PANG Liang-jun YANG Qi XIE Si-si ZHU Dao-ming |
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| Affiliation: | PANG Liang-jun,YANG Qi,XIE Si-si,ZHU Dao-ming,People's Forth Hospital of Hefei,Hefei 230022,China |
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| Abstract: | Objective:To explore the efficacy and safety of ziprasidone in the treatment of schizophrenia. Method:Sixty schizophrenia patients who met with the diagnostic criteria of CCMD-3 were randomly assigned to ziprasidone group or clozapine group and then received 6 weeks treatment.The efficacy and side effects were evaluated with the positive and negative symtom scale(PANSS) and treatment emergent symptoms scale(TESS) before and at the end of 2nd,4th and 6th weeks treatment. Results:No significant difference was... |
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| Keywords: | zprasidone clozapine schizophrenia |
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