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老年恶性肿瘤患者外周血T淋巴细胞检测及意义
引用本文:党连生,刘美玲,刘少旋. 老年恶性肿瘤患者外周血T淋巴细胞检测及意义[J]. 包头医学院学报, 2014, 0(5): 37-38
作者姓名:党连生  刘美玲  刘少旋
作者单位:内蒙古包头医学院第一附属医院,内蒙古 包头,014010
摘    要:
目的:了解老年恶性肿瘤患者的细胞免疫功能状况,为肿瘤的治疗及预防提供参考。方法:用流式细胞仪分别对肺癌、消化道肿瘤、乳腺癌患者及健康对照组外周血总T细胞、Th、Ts、Th/Ts细胞进行检测,用SPSS 17.0软件对各组细胞的Th数值及Th/Ts比值进行统计学分析。结果:Th细胞数及Th/Ts比值在肺癌、消化道肿瘤以及乳腺癌患者均明显低于正常对照组(P〈0.05)。结论:老年恶性肿瘤患者的细胞免疫功能处于抑制状态。

关 键 词:老年恶性肿瘤  T细胞亚群  流式细胞仪

The Detection and Significance of T lymphocyte in the Peripheral Blood of Elderly Patients with Malignant Tumor
DANG Liansheng,LIU Meiling,LIU Shaoxuan. The Detection and Significance of T lymphocyte in the Peripheral Blood of Elderly Patients with Malignant Tumor[J]. Journal of Baotou Medical College, 2014, 0(5): 37-38
Authors:DANG Liansheng  LIU Meiling  LIU Shaoxuan
Affiliation:(Department of Geratology, the First Affiliated Hospital of Baotou Medical College, Baotou 014010, China )
Abstract:
Objective:To analyze the status of cellular immune function in elderly patients with malignant tumors so as to provide a reference for tumor therapy. Methods:Flow cytometry was used to detect peripheral blood T(TT),Th,Ts and Th/ Ts cells,respectively,in patients with lung cancer,gastrointestinal cancer and breast cancer and healthy controls,with Th count and the ratio of Th/ Ts in each group analyzed by SPSS 17. 0. Results:The count of Th cells and the ratio of Th/ Ts in patients with lung cancer,gastrointestinal cancer and breast cancer were significantly lower than those in the control group( P〈0. 05). Conclusion:Cellular immune function in elderly patients with malignant tumors is in the state of suppression.
Keywords:Malignant tumor  T - cell subsets  Flow cytometry
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