Abstract: | The number of immunoglobulin- (Ig-) positive lymphocytes and of their precursors in mouse bone marrow was investigated 6 and 36 h after treatment with hydroxyurea. The number of Ig-positive B-cells in bone marrow so treated was increased a little, whereas dividing and nondividing precursors of B-lymphocytes were virtually absent, with the exception of stem cells.Laboratory of Cytochemistry and Molecular Biology of Immunogenesis, Institute of Human Morphology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR A. P. Avtsyn.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 86, No. 10, pp. 460–462, October, 1978. |