后循环缺血患者的听觉诱发电位变化

目的探讨后循环缺血患者的脑血流动力学听觉诱发电位改变。方法对110例经临床确诊的后循环缺血(PCI)患者依据临床症状及CT/MRI检查结果分为梗死组(48例)和非梗死组(62例),均进行脑干听觉诱发电位(BAEP)检查,并与50例健康对照组进行对比。结果 110例PCI患者BAEP异常86例,异常率78.2%,主要异常表现为:Ⅰ、Ⅲ、Ⅴ波的潜伏期和Ⅲ～Ⅴ潜伏间期延长,表现以脑干型为主(33/110,30%),高于内耳型(24/110,21.9%)和混合型(29/110,26.4%)。梗死组Ⅲ波潜伏期(4.12±0.23)较非梗死组(3.98±0.21)显著延长(P<0.05),梗死组Ⅴ波潜伏期(6.04±0.25)较非梗死组(5.75±0.39)显著延长(P<0.01),梗死组Ⅲ～Ⅴ潜伏间期(2.08±0.23)较非梗死组(1.77±0.31)显著延长(P<0.01)。结论BAEP能灵敏地检测出后循环缺血患者的神经电生理异常,其异常程度可部分反应病情的严重程度,对后循环缺血的诊断和病情评估,提供重要的参考。

Changes of Brain Auditory Evoked Potential in Patients with Posterior Circulation Ischemia

Objective To investigate the changes of Electroneurophysiology in patients with posterior circulation ischemia(PCI).Methods 110 patients with PCI which been divided in infarct group(48 cases) and non-infarct group(62 cases) were evaluated by brain auditory evoked potential(BAEP)compared with controls(50 cases).Results In all 110 PCI patients the abnormalities of BAEP were detected in 86cases(78.2%).The main abnormal findings of BAEP included prolonged peak latency(PL) of Ⅰ.Ⅲ.Ⅴ waves and prolonged interpeak latency(IPL) of Ⅲ~Ⅴ wave.The brain stem type(33/110,30%)abnormality was higher than the type of inner-ear type(24/110,21.9%)and the mixied type(29/110,26.4%).The PL of Ⅲ wave in infarction group(4.12±0.23) was significantly prolonged than non-infarction group(3.98±0.21)(P<0.05);The PL of Ⅴ wave in infarction group(6.04±0.25) was significantly prolonged than non-infarction group(5.75±0.39)(P<0.01);The IPL of Ⅲ~Ⅴ wave in infarction group(2.08±0.23) was significantly prolonged than non-infarction group(1.77±0.31)(P<0.01).Conclusion BAEP could detected the electro neurophysiologic abnormalities sensitively in patients with PCI,BAEP had played a very important role on the early diagnosis,severity assessment and prognosis indicate in PCI.