| 慢性肾衰竭患者代谢性酸中毒与营养不良-炎症反应综合征 |
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| 引用本文： | 朱浪静,阳晓,余学清.慢性肾衰竭患者代谢性酸中毒与营养不良-炎症反应综合征[J].国外医学：内科学分册,2007,34(1):52-56. |
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| 作者姓名： | 朱浪静 阳晓 余学清 |
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| 作者单位： | 中山大学附属第一医院肾内科,卫生部及广东省肾脏病重点实验室,广州510080 |
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| 基金项目： | 国家自然科学基金
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高等学校博士学科点专项科研项目
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广东省科技攻关计划 |
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| 摘 要： | 代谢性酸中毒(MA)是慢性肾衰竭患者常出现的临床表现,可能与蛋白质-热能营养不良(PEM)和炎症有关,后两者合称为营养不良-炎症反应综合征(MICS).酸血症是引起慢性肾衰竭患者预后不良和死亡的重要原因.然而新近许多流行病学的研究显示慢性肾衰竭患者MA的"逆流行病学"现象.本文就MA与慢性肾衰竭患者MICS关系的研究进展作一综述.
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| 关 键 词： | 慢性肾衰竭 代谢性酸中毒 营养不良-炎症反应综合征 |
| 文章编号： | 1004-2369（2007）01-0052-05 |
| 修稿时间： | 2006-01-252006-10-28 |
Metabolic acidosis and malnutrition-inflammation complex syndrome in patients with chronic renal failure |
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| ZHU Lan-jing,YANCT Xiao,YU Xue-qing.Metabolic acidosis and malnutrition-inflammation complex syndrome in patients with chronic renal failure[J].Foreign Medical Sciences(Section of Internal Medicine),2007,34(1):52-56. |
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| Authors: | ZHU Lan-jing YANCT Xiao YU Xue-qing |
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| Institution: | Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China. |
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| Abstract: | Metabolic acidosis(MA) is a common clinical manifestation in patients with chronic renal failure(CRF).and may be linked to protein-energy malnutrition(PEM) and inflammation,both of which are also known as malnutrition-inflammation complex syndrome(MICS).Acidemia is believed to be an important cause of bad prognosis and death in pateints with CRF.However,many recent epidemiologic studies have indicated the reveres epidemiology of MA in patients with CRF.This article reviews the advanced researches on the relationship between MA and MICS in patients with CRF. |
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| Keywords: | Chronic renal failure Metabolic acidosis Malnutrition-inflammation complex syndrome |
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