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Differences in the Intracellular Killing of Proteinase-Positive and Proteinase-Negative Candida albicans Strains by Granulocytes/Unterschiede in der intrazellulären Abtötung von Proteinasepositiven und -negativen Candida-albicans-Stämmen durch Granulozyten |
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| Authors: | Th. Walther,M. Rytter,Christina Schö nborn,and U.-F. Haustein |
| Affiliation: | Department of Dermatology, School of Medicine, Karl-Marx-University (Director: MR Prof. Dr. sc. med. U.-F. Haustein) |
| Abstract: | Summary: Neutrophil granulocytes isolated from healthy volunteers were found to kill proteinase-producing Candida albicans strains more effectively than proteinase negative strains in vitro (p < 0.01).The proportion was one Candida cell to one, three or five granulocytes. Zusammenfassung: Durch neutrophile Granulozyten gesunder Probanden werden in vitro bei einem Verhältnis von einer Candidazelle zu einem, drei oder fünf Granulozyten Proteinase-positive Candida-albicans-Stämme besser abgetötet als Proteinase-negative Stämme (p < 0,01). |
| Keywords: | Candida albicans proteinase activity phagocytosis killing by granulocytes Candida albicans Proteinasebildung Phagozytose Abtötung durch Granulozyten |