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多种措施对耐甲氧西林金黄色葡萄球菌感染的干预效果分析
引用本文:张俊,;张汝学. 多种措施对耐甲氧西林金黄色葡萄球菌感染的干预效果分析[J]. 中国医药, 2014, 0(9): 1372-1375
作者姓名:张俊,  张汝学
作者单位:[1]兰州军区总医院院部,730050; [2]兰州军区总医院药剂科,730050
摘    要:目的:评价多种措施干预对耐甲氧西林金黄色葡萄球菌(MRSA)医院感染的防控效果。方法对实施多种措施(集中消毒、中心供应、感染防控实时监控和定期通报等)干预前(2011年1月1日至2011年12月31日)、后(2012年1月1日至2013年8月31日)兰州军医总医院住院患者中发生MRSA医院感染患者各117例的感染发生率、感染部位与科室分布、标本来源及干预效果进行调查分析。结果干预前医院感染例次率为2.0%(983/50054),其中MRSA感染率为0.2%(119/50054),占医院感染例次的12.1%。干预后医院感染例次率为1.4%(1592/111060),其中MRSA感染例次率为0.1%(117/111060),占医院感染例次的7.4%。干预前,MRSA医院感染较高的科室是急诊科、神经内科、综合重症监护病房(ICU)、神经外科、呼吸科,分别占28.6%(34/119)、21.8%(26/119)、14.3%(17/119)、10.0%(12/119)、5.0%(6/119);干预后神经内科8.5%(10/117)和综合ICU7.7%(9/117)取得较为显著的控制效果。感染部位以下呼吸道为首,占87.7%(207/236),其次是手术伤口、泌尿道、血液感染,分别占5.9%(14/236)、2.1%(5/236)、2.1%(5/236)。结论以集中消毒、中心供应为主的多种措施干预对MRSA医院感染具有较好的防控作用。

关 键 词:耐甲氧西林金黄色葡萄球菌  医院感染  感染控制  干预

Effects of multiple interventions on methicillin-resistant staphylococcus aureus hospital infection
Affiliation:Zhang Jun , Zhang Ruxue. ( Ministry of Lanzhou General Hospital of People's Liberation Army, Lanzhou 730050, China)
Abstract:Objective To evaluate the implementation of a variety of interventions for prevention and con -trol of methicillin-resistant staphylococcus aureus( MRSA) hospital infection .Methods The MRSA infectious rate , sites of infection , distribution departments and the specimen source before multiple interventions ( centralized steri-lization, central supply , infection prevention and control of real-time monitoring and regular reporting , etc.) of 177 cases before and after multiple interventions were compared and analyzed .Results Before multiple interven-tions, the occurrence rate of hospital infection was 2.0%(983 cases of times) and the MRSA infections rate was 0.2%(119 cases of times).However, the rate of hospital infection was 1.4%(1 592 cases of times) and MRSA infections rate was 0.2% (119 cases of times) after multiple interventions.Before the intervention, the depart-ments suffering from MRSA infection were mainly the departments of emergency , neurology , general ICU , neuro-surgery and respiratory, accounting for 28.6% (34/119),21.8% (26/119),14.3% (17/119),10.0% (12/119),5.0% (6/119), respectively.The top infectious sites of MRSA infections included the lower respiratory tract 87.7%(207/236), the surgical wounds 5.9% (14/236), urinary tract 2.1%(5/236) and blood infec-tions 2.1%(5/236).Conclusion Multiple interventions such as centralized disinfection , central supplies can have a good effect on the prevention and control of MRSA hospital infection .
Keywords:Methicillin-resistant staphylococcus aureus  Hospital infection  Infection control  Intervention
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