胰腺坏死与器官功能不全

目的探讨胰腺坏死状况及合并感染与器官功能不全的关系。方法回顾性分析了我院１９９３～１９９７年间收治的经动态增强ＣＴ或手术证实有胰腺坏死的６７例重症胰腺炎患者，感染性胰腺坏死根据ＣＴ引导细针穿刺或手术中涂片培养证实。结果发生器官功能不全者３５例（５２．２％），无器官功能不全者３２例，胰腺坏死部位和坏死面积对器官功能不全的发生无显著性影响；胰腺坏死合并感染患者发生器官功能不全率为７５％，无感染者为４５．１％，两者间差异有显著性意义。结论胰腺坏死合并感染对器官功能不全的发生有明显的影响，而坏死部位和范围等没有明显影响。

Pancreatic necrosis and organ failure

Objective This study are to determine the relationship between pancreatic necrosis and organfailure in severe acute pancreatihs. Methods Sixty-seven patients with necrotizing pancreatitis from 1993 to 1997.were retrospectively studied. Pancreatic necrosis was identified by dynamic contrast-enhanced computerized tomog raphy and operation. Infectious necrosis was confirmed by Gram's stain and culture of CT-guided percutaneous astyrates and pancreatic tissue e debrided at surgery. Results Organ failure was present in 35 patients (52. 2%).There was no difference in the extent and the location Of necrosis between patients with organ failure and those with out it. There were more patients suffered from organ failure in the group with infectious necrosis(75%) than thosein the group with sterile necrosis(45.1%). Conclusion This study suggests that infectious necrosis correlateswith organ failure. There is no correlation for extent and location of necrosis with organ failure.