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Dysregulation of the TGF-β Postreceptor Signaling Pathway in Cell Lines Derived from Primary or Metastatic Ovarian Cancer
作者单位:Department of Obstetrics and Gynecology,Anderson Cancer Center,Southwestern Medical Center,Department of Obstetrics and Gynecology,Department of Obstetrics and Gynecology,Department of Obstetrics and Gynecology,Department of Obstetrics and Gynecology Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,Taxas,USA,Taxas,USA,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030
摘    要:
Transforminggrowthfactor β (TGF β)isamul tifunctionalhomodimeric polypeptide ,whichmaycausecellcyclearrest ,terminaldifferentiation ,orapoptosisandactsasanegativegrowthregulatorinmostnormalepithelialandendothelialcelltypes ,whereasmostmalignantcelllines…

关 键 词:Transforming growth factor b  CDC25A  Smad4  C myc  TβRⅡ  ovarian cancer cells
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