t-DARPP regulates phosphatidylinositol-3-kinase-dependent cell growth in breast cancer |
| |
| Authors: | Bhavatarini Vangamudi Dun-Fa Peng Qiuyin Cai Wael El-Rifai Wei Zheng Abbes Belkhiri |
| |
| Affiliation: | (1) Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA;(2) Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA |
| |
| Abstract: | ![]()
Background Recent reports have shown that t-DARPP (truncated isoform of DARPP-32) can mediate trastuzumab resistance in breast cancer cell models. In this study, we evaluated expression of t-DARPP in human primary breast tumors, and investigated the role of t-DARPP in regulating growth and proliferation in breast cancer cells. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
