Chemical characterization of the parasitophorous vacuole membrane antigen QF 116 from Plasmodium falciparum. |
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| Authors: | U Kara B Murray C Pam J Lahnstein H Gould C Kidson A Saul |
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| Affiliation: | Queensland Institute of Medical Research, Herston, Brisbane, Australia. |
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| Abstract: | On the basis of amino acid sequencing and immunological cross-reactivity, the Plasmodium falciparum parasitophorous vacuole antigens QF116 and exp-1/CRA are apparently identical. The epitope recognized by an inhibitory monoclonal antibody directed against QF116 is located proximal to the C-terminus of the protein. The QF116 protein is processed during maturation by the cleavage of a 22-amino-acid signal peptide and acylated as measured by labeling with myristic acid. |
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