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Design of the Resistance and Endurance exercise After ChemoTherapy (REACT) study: A randomized controlled trial to evaluate the effectiveness and cost-effectiveness of exercise interventions after chemotherapy on physical fitness and fatigue |
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| Authors: | Caroline S Kampshoff Laurien M Buffart Goof Schep Willem van Mechelen Johannes Brug Mai JM Chinapaw |
| Affiliation: | 1.EMGO Institute for Health and Care Research, department of Public and Occupational Health,VU University Medical Center,Amsterdam,The Netherlands;2.EMGO Institute for Health and Care Research, department of Epidemiology and Biostatistics,VU University Medical Center,Amsterdam,The Netherlands;3.Máxima Medical Center, department of Sports Medicine,Veldhoven,The Netherlands |
| Abstract: | BackgroundPreliminary studies suggest that physical exercise interventions can improve physical fitness, fatigue and quality of life in cancer patients after completion of chemotherapy. Additional research is needed to rigorously test the effects of exercise programmes among cancer patients and to determine optimal training intensity accordingly. The present paper presents the design of a randomized controlled trial evaluating the effectiveness and cost-effectiveness of a high intensity exercise programme compared to a low-to-moderate intensity exercise programme and a waiting list control group on physical fitness and fatigue as primary outcomes. |
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