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| 脑脊液中抗BCG抗体分泌细胞测定对结核性脑膜炎鉴别诊断价值的研究 | |
| 引用本文： | 王少石 高晓玲 刘晓娟. 脑脊液中抗BCG抗体分泌细胞测定对结核性脑膜炎鉴别诊断价值的研究[J]. 中国神经免疫学和神经病学杂志, 1995, 2(3): 153-155 |
| 作者姓名： | 王少石 高晓玲 刘晓娟 |
| 作者单位： | [1]上海市第四人民医院神经内科，上海200081 [2]贵州省黔南医院神经科 |
| 摘 要： | 用酶联免疫斑点(Elispot)法，将BCG作为抗原，对16例结核性脑膜炎33例次脑脊液中淋巴细胞分离培养，从体外检测BCG特异性IgG抗体分泌细胞，结果表明总阳性率为91．7％，对照组(其它颅内炎症)18例共22例次检测无1例阳性。提示采用本法对结核性脑膜炎进行诊断具有特异性。 |
| 关 键 词： | 结核性脑膜炎 BCG 脑脊液 抗B 分泌细胞 诊断 抗体 斑点 特异性 分离培养 |
Studied on Differential Diagnosis of Tuberculous Meningitis by Detection of Anti-BCG Secreting Cells in Cerebrospinal Fluid |
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| Wang Shaoshi,Gao Xiaoling,Liu Xiaojuan. Studied on Differential Diagnosis of Tuberculous Meningitis by Detection of Anti-BCG Secreting Cells in Cerebrospinal Fluid[J]. Chinese Journal of Neuroimmunology and Neurology, 1995, 2(3): 153-155 | |
| Authors: | Wang Shaoshi Gao Xiaoling Liu Xiaojuan |
| Abstract: | By detection of anti-BCG secretion cells in cerebrospinal fluid for differential diagnosis tuberculous meningitis 15(93.8%)were positive from 16 patients with tuberculous meningitis at admitted to hospital,10(83.3%)were positive from 12 patients after one month treated by anti-tuberculous drugs,5(62.5%)were positive from 8 patients after three month. Cells secreting anti-BCG IgG hadn't been detected in 18 patients with other intracranial inFection.Our results suggested that this assay could be applied in clinic for differential diagnosis of tuberculous meningitis. |
| Keywords: | tuberculous meningitis antibody secreting cells |
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