| 小剂量沙利度胺联合中药治疗白塞病的疗效 |
| |
| 引用本文： | 林志翔,姜元芹,戴益琛,戴禄寿,陈章兴,孙华瑜. 小剂量沙利度胺联合中药治疗白塞病的疗效[J]. 实用药物与临床, 2011, 14(1): 75-77 |
| |
| 作者姓名： | 林志翔 姜元芹 戴益琛 戴禄寿 陈章兴 孙华瑜 |
| |
| 作者单位： | 1. 中国人民解放军第174医院,厦门,361003
2. 厦门市第一医院,厦门,361004 |
| |
| 摘 要： | 目的观察小剂量沙利度胺治疗白塞病的临床疗效。方法收集2005年9月起,在我院门诊及住院的符合白塞病诊断标准的患者38例,随机分为低剂量组和高剂量组。高剂量组19例,给予沙利度胺,100mg/次,每晚1次,并给予对症治疗;低剂量组19例,均给予沙利度胺50 mg/次,每晚1次,正清风痛宁缓释片120mg/次,2次/d。疗程半年。治疗前后主要观察指标包括临床症状的发生频率和程度等,次要观察指标包括血沉、C反应蛋白,以及用药安全情况等。结果低剂量组除1例出现不良反应未坚持治疗外,余18例患者治疗半年后,多个主要观察指标中均有不同程度的改进,且疗效优于高剂量组,总有效率94.4%,但两组差异无统计学意义(P>0.05),且复发减少。常见的不良反应为困倦、头晕、口干和便秘。结论在正清风痛宁缓释片配合治疗下,小剂量沙利度胺治疗白塞病患者,效果显著,毒副作用小。
|
| 关 键 词： | 白塞病 沙利度胺 |
Clinical effects of low dose thalidomide combined with Chinese medicine in treatment of Bechet''s disease |
| |
| LIN Zhi-xiang,JIANG Yuan-qin,DAI Yi-chen,DAI Lu-shou,CHEN Zhang-xing,SUN Hua-yu. Clinical effects of low dose thalidomide combined with Chinese medicine in treatment of Bechet''s disease[J]. Practical Pharmacy and Clinical Remedies, 2011, 14(1): 75-77 |
| |
| Authors: | LIN Zhi-xiang JIANG Yuan-qin DAI Yi-chen DAI Lu-shou CHEN Zhang-xing SUN Hua-yu |
| |
| Affiliation: | LIN Zhi-xiang1,JIANG Yuan-qin1,DAI Yi-chen1,DAI Lu-shou1,CHEN Zhang-xing1,SUN Hua-yu2(1.174 Hospital of PLA,Xiamen 361003,China,2.First Hospital of Xiamen,Xiamen 361004,China) |
| |
| Abstract: | Objective To investigate the effect of low dose thalidomide combined with Chinese medicine for treating patients with Bechet's disease. Methods 38 patients with Bechet's disease were divided into two groups according to resourceful principle,group A(19 cases)was given thalidomide(100 mg/d)and expectant treatment;group B(19 cases)was given thalidomide(50 mg/d)and Zhengqing fengtongning(120 mg,twice a day).The course of treatment was half a year. Results After treating for a course,all the patients' indexes h... |
| |
| Keywords: | Bechet's disease Thalidomide |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
