Abstract: | The effects of hyperthermic treatment on some intracellular components and on the general morphology of Chinese hamster V79 fibroblasts have been studied. After 1 h of heating at 42°C cells show small interruptions of the plasma membrane, dilation of the mitochondrial cristae and dissociation of the polyribosomes. These modifications become progressively more pronounced after 1 or 3 h treatment at 43°C. Severe alterations in the general morphology of the cells are evident after 1 h heating at 45°C. |