呼吸道念珠菌感染112例分析

目的:探讨肺部念珠菌感染的危险因素、临床诊断、治疗及预后.方法:回顾性分析112例呼吸道念珠菌感染的临床资料.结果:呼吸道念珠菌感染的危险因素为:长期使用广谱抗菌药物及糖皮质激素、免疫抑制剂,以肾移植术后、慢性阻塞性肺疾病、支气管扩张、白血病等慢性基础疾病病人多见.结论:合理使用抗菌药物及糖皮质激素、免疫抑制剂,以及早期诊断和及时抗真菌治疗,是降低呼吸道念珠菌感染并降低病死率的重要措施.

112 cases of candidosis infection in the respiratory tract

Objective To discuss the clinical features, therapeutic outcome, prognosis and the major risk factors of candidosis in the respiratory tract. Method 112 cases with candidosis in the respiratory tract were retrospectively analyzed. Results The risk factors for candidosis i n the respiratory were related to the treatments with broad spectrum antibiotics , cortical hormone and immunosuppressive agents. The aged patients and the patie nts with chronic basic diseases were susceptible to candidosis. Conclusion Reasonable use of antibiotics, cortical hormone and immunosuppressive agen ts as well as early diagnosis and treating fungus infection are important measur es to decrease the incidence and the mortality of candidosis in the respiratory tract.