Treatment of Mood and Depressive Disorders With Complementary and Alternative Medicine: Efficacy Review |
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| Authors: | Jasmine B.R. Cutler PharmD Olivia Pane PharmD CDCES Simran K. Panesar PharmD Wendy Updike PharmD BCPS CDCES Thea R. Moore PharmD BCPP |
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| Affiliation: | 1. Taneja College of Pharmacy, University of South Florida, Tampa, Florida, United 2. States;3. North Florida / South Georgia Veterans System, Gainsville, Florida, United |
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| Abstract: | ![]()
There has been a steady increase in people with symptoms of depression over the past several years (since 2011). The further increase in stress and depression in the early part of the COVID-19 pandemic was accompanied by an increase in unmet mental health needs. Many have turned to complementary and alternative medicine (CAM) therapies such as bright-light therapy, yoga, meditation, and dietary supplements like St. John's wort or folic acid. The reliability of evidence for use of CAM therapies for depression has remained low. There are few randomized controlled trials (RCTs) in the current literature and poor methodology in many of the trials that are available. This state of the science review examines current published guidelines, meta-analyses, systematic reviews, and RCTs regarding use of CAM therapies in the management of depression. |
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| Keywords: | complementary and alternative medicine depression major depressive disorder acupuncture exercise light therapy mindfulness/meditation yoga DHEA folate omega-3 fatty acids S-adenosylmethionine St. John's wort |
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