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Radiation necrosis in renal cell carcinoma brain metastases treated with checkpoint inhibitors and radiosurgery: An international multicenter study
Authors:Eric J. Lehrer MD  MS  Jason Gurewitz DO  Kenneth Bernstein MS  Dev Patel  Douglas Kondziolka MD  Ajay Niranjan MD  MBA  Zhishuo Wei MSc  L. Dade Lunsford MD  Timothy D. Malouff MD  Henry Ruiz-Garcia MD  Samir Patel MD  Phillip A. Bonney MD  Lindsay Hwang MD  Cheng Yu PhD  Gabriel Zada MD  David Mathieu MD  Claire Trudel MD  Rahul N. Prasad MD  Joshua D. Palmer MD  Brianna M. Jones MD  Sonam Sharma MD  Kareem R. Fakhoury MD  Chad G. Rusthoven MD  Christopher P. Deibert MD  Piero Picozzi MD  Andrea Franzini MD  Luca Attuati MD  Cheng-Chia Lee MD  PhD  Huai-Che Yang MD  Manmeet S. Ahluwalia MD  MBA  Jason P. Sheehan MD  PhD  Daniel M. Trifiletti MD
Affiliation:1. Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York;2. Department of Radiation Oncology, NYU Langone Medical Center, New York, New York;3. Department of Neurosurgery, NYU Langone Medical Center, New York, New York;4. Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania;5. Department of Radiation Oncology, Mayo Clinic, Jacksonville, Florida;6. Division of Radiation Oncology, Department of Oncology, University of Alberta, Edmonton, Alberta, Canada;7. Department of Neurosurgery, University of Southern California, Los Angeles, California;8. Department of Radiation Oncology, University of Southern California, Los Angeles, California;9. Department of Neurosurgery, Université de Sherbrooke, Centre de Recherche du CHUS, Quebec, Quebec, Canada;10. Department of Medicine, Université de Sherbrooke, Centre de Recherche du CHUS, Quebec, Quebec, Canada;11. Department of Radiation Oncology, Ohio State University Wexner Medical Center, Columbus, Ohio;12. Department of Radiation Oncology, University of Colorado, Denver, Colorado;13. Department of Neurological Surgery, Emory University, Atlanta, Georgia;14. Department of Neurosurgery, Humanitas Research Hospital–IRCCS, Rozzano, Italy;15. Department of Neurosurgery, Neurological Institute, Taipei Veteran General Hospital, Taipei, Taiwan;16. Department of Medical Oncology, Miami Cancer Institute, Miami, Florida;17. Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia
Abstract:
Keywords:brain neoplasms  carcinoma  combined modality therapy  immune checkpoint inhibitors  necrosis  radiation injuries  radiosurgery  renal cell
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