以腹型为首发表现的儿童过敏性紫癜临床分析

目的 了解以腹部症状为首发表现的儿童过敏性紫癜(HSP)临床特征,并探讨胃镜和全腹计算机断层扫描(CT)对其早期诊断价值.方法 选取2017-09-01-2019-08-31就诊于中国医科大学附属盛京医院小儿消化内科以腹痛等消化道表现为首发症状的腹型HSP住院患儿169例为观察组,以皮疹为首发症状142例为对照组,对临...

Clinical analysis of Henoch-Schonlein purpura in children with abdominal symptoms as the first manifestation

Objective To investigate the clinical features of Henoch-Schonlein purpura(HSP)with abdominal symptoms as the first manifestation,and to explore the value of gastroscopy and abdominal CT in its early diagnosis.Methods 169 hospitalized children with HSP with abdominal pain as the first manifestation were selected as the observation group.142 patients with rash as the first symptom were selected as the control group.The clinical data were analyzed.Results The observation group had a lower incidence of prodromal infection and/or positive etiology(P<0.05),33 cases showed no rash(19.53%).More children in observation group experienced vomiting(P<0.05).The white blood cell count,CRP,platelet count,D-dimer and fecal occult blood positive rate were higher in observation group(P<0.05),but Albumin,IgA and C3 were lower(P<0.05).There was no significant difference in gastrointestinal bleeding,procalcitonin,specific allergen positivity rate,immunoglobulin E,urine protein and erythrocyte elevation(P>0.05).There was no difference in positive detection rate between gastroscopy and abdominal CT(P>0.05).There was no difference in hormone sensitivity and the incidence of purpura nephritis between two groups(P>0.05),but recurrence rate was higher in observation group(P<0.05).Conclusion Children with HSP with abdominal pain as the first manifestation are more prone to vomiting,and some children may not have rashes.Their white blood cell count,CRP,platelet count,D-dimer level,positive rate of fecal occult blood,the incidence of hypoalbuminemia and recurrence were higher.There was no significant difference in the positive detection rate of gastroscopy and abdominal CT.