稳定性及不稳定性心绞痛患者冠状动脉病变血管内超声的对比研究

目的探讨稳定性心绞痛(stable angina,SA)及不稳定性心绞痛(unstable angina,UA)患者冠脉斑块在血管内超声(intravascular ultrasound,IVUS)下的表现特征.方法对经冠状动脉造影确诊的7例SA患者、29例UA患者的共55支病变冠脉行IVUS检查.结果SA组主要为稳定型、纤维性斑块,UA组主要为不稳定型、脂质性斑块.钙化性斑块在两组中的分布类似.UA组偏心指数(EI)显著高于SA组(P＜0.05),有以正重构为主的趋势.SA组的血管外弹力膜面积显著高于UA组(P＜0.01).结论SA患者及UA患者的冠脉斑块在性质及结构特点上差异显著.

Comparison of intravascular ultrasound imaging between patients with stable and unstable angina

Objective To investigate the morphological features of atherosclerotic plaques by intravascular ultrasound(IVUS) in patients with stable angina(SA) and patients with unstable angina(UA).Methods Seven SA patients and 29 UA patients admitted to our hospital from Aug 2004 to Jan 2005 were definitely diagnosed by coronary angiography(CAG),whose 55 impaired coronary arteries underwent IVUS to analyze the coronary lesions.Results SA patients mainly had stable and fibrous plaques,while UA patients mainly had unstable and soft lipid plaques(P<0.01).Calcific plaques were found in SA patients as well as UA patients,with no statistical difference(P>0.05).Eccentric index(EI) was higher in UA patients than SA patients(P<0.05),and coronary segments in UA patients were prone to positive remodeling.EEMA was larger in SA patients than VA patients(P<0.01).Conclusion The morphological features of coronary artery lesions in UA patients significantly differ from those in SA patients.