| 正交试验法优选火麻仁油中大麻酚类化合物的提取工艺 |
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| 引用本文： | 张岗,郭江宁,毕开顺.正交试验法优选火麻仁油中大麻酚类化合物的提取工艺[J].中药材,2005,28(5):417-418. |
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| 作者姓名： | 张岗 郭江宁 毕开顺 |
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| 作者单位： | 1. 东北大学理学院,辽宁沈阳,110004
2. 沈阳药科大学药学院,辽宁沈阳,110016 |
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| 摘 要： | 目的:优选火麻仁油中大麻酚类化合物的提取工艺.方法:采用正交实验的方法,以大麻酚和Δ9-四氢大麻酚的含量为指标,来考察提取时间、提取次数和溶剂量对火麻仁油中大麻酚类化合物的提取效果的影响.结果:提取时间每次15 min,提取两次,每次加5 mL溶剂为最佳提取工艺.结论:该工艺合理、稳定可行,且方法简便.
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| 关 键 词： | 火麻仁油 正交设计 大麻酚类化合物 |
| 修稿时间： | 2004年9月22日 |
Study on the Extraction Process for Cannabinoids in Hemp Seed Oil by Orthogonal Design |
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| Zhang Gang,Guo Jiangning,Bi Kaishun.Study on the Extraction Process for Cannabinoids in Hemp Seed Oil by Orthogonal Design[J].Jorunal of Chinese Medicinal Materials,2005,28(5):417-418. |
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| Authors: | Zhang Gang Guo Jiangning Bi Kaishun |
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| Institution: | North-east University, Shenyang. |
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| Abstract: | OBJECTIVE: To select the optimum extracting procedure for cannabinoids from hemp seed oil. METHODS: The optimum extracting procedure was selected with the content of cannabinol and delta9-tetrehydrocannabinol from hemp seed oil by orthogonal test design. We have examined three factors that may influence the extraction rate: the time of extraction, the times of extraction and the amount of methanol. RESULTS: The optimum extraction condition was adding 5 ml, two times amount of methanol into hemp seed oil for 15 min. CONCLUSION: The above extraction process gave the most rational, stable, feasible and satisfactory results. The method is convenient. |
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| Keywords: | Hemp seed oil Orthogonal experimental design Cannabinoids |
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